Publication:
Enhancing effects of rodent malaria on aflatoxin B1-induced hepatic neoplasia

Issued Date

1986-10-01

Resource Type

Article

ISSN

14321335
01715216

DOI

10.1007/BF00404403

Other identifier(s)

2-s2.0-0022452751

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Cancer Research and Clinical Oncology. Vol.112, No.2 (1986), 177-179

Suggested Citation

S. Angsubhakorn, P. Sathiropas, N. Bhamarapravati Enhancing effects of rodent malaria on aflatoxin B1-induced hepatic neoplasia. Journal of Cancer Research and Clinical Oncology. Vol.112, No.2 (1986), 177-179. doi:10.1007/BF00404403 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/9665

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Title

Enhancing effects of rodent malaria on aflatoxin B1-induced hepatic neoplasia

Author(s)

S. Angsubhakorn
 P. Sathiropas
 N. Bhamarapravati

Other Contributor(s)

Mahidol University
 Khon Kaen University

Abstract

The interaction between aflatoxin and malaria was tested for its usefulness as a model for hepatic tumor induction in rats. Male Buffalo rats which received aflatoxin B 1 (AFB 1 ) followed by Plasmodium berghei infection developed more preneoplastic lesions in the liver compared to those given AFB 1 alone. No preneoplastic lesions were found in the liver of control and malarial-treated animals. These findings suggest that the malarial parasite facilitates liver tumor development initiated by AFB 1 in rats. © 1986 Springer-Verlag.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/9665

Collections

Scopus 1969-1990