Publication: Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)
Issued Date
2020-10-01
Resource Type
ISSN
18781683
14730502
14730502
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2-s2.0-85092514720
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Mahidol University
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SCOPUS
Bibliographic Citation
Transfusion and Apheresis Science. Vol.59, No.5 (2020)
Suggested Citation
Akihiro Takeshita, Hiroko Watanabe, Chiaki Yamada, Veera Sekaran Nadarajan, Parichart Permpikul, Attapong Sinkitjasub, Chan Pui Ha Natalie, Shuming Zhao, Kyou Sup Han, Dae Won Kim, Jang Soo Suh, Hyun Ok Kim, Kinuyo Kawabata, Ken Ishimaru, Naoki Ohtomo, Naotomo Yamada, Yutaka Tomoda, Kimiko Yurugi, Hitoshi Ohto Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP). Transfusion and Apheresis Science. Vol.59, No.5 (2020). doi:10.1016/j.transci.2020.102944 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/60590
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Title
Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP)
Author(s)
Other Contributor(s)
Japanese Red Cross Medical Center
Kyungpook National University Hospital
Prince of Wales Hospital Hong Kong
Third Military Medical University
Saga University
Yonsei University College of Medicine
SungKyunKwan University, School of Medicine
Taksin Hospital
University of Malaya Medical Centre
Faculty of Medicine, Siriraj Hospital, Mahidol University
Kyoto University Hospital
Asahikawa Medical University
Hamamatsu University School of Medicine
Tokyo Medical and Dental University
Fukushima Medical University
Seegene Medical Foundation
Kyungpook National University Hospital
Prince of Wales Hospital Hong Kong
Third Military Medical University
Saga University
Yonsei University College of Medicine
SungKyunKwan University, School of Medicine
Taksin Hospital
University of Malaya Medical Centre
Faculty of Medicine, Siriraj Hospital, Mahidol University
Kyoto University Hospital
Asahikawa Medical University
Hamamatsu University School of Medicine
Tokyo Medical and Dental University
Fukushima Medical University
Seegene Medical Foundation
Abstract
© 2020 Elsevier Ltd As an East-Asian international study, we evaluated erythrocyte alloimmunity by gender and history of transfusion or pregnancy. In total, data from more than 1,826,000 patients were analyzed, from whom 26,170 irregular erythrocyte antibodies were detected in 22,653 cases. Antibody frequencies in these cases were as follows: anti-E, 26.8%; anti-Lea, 20.0%; anti-P1, 7.1%; anti-M, 6.4%; anti-Mia, 5.6%; anti-c + E, 5.6%; anti-Leb, 4.6%; anti-D, 2.8%; anti-Fyb, 2.6%; anti-Lea+Leb, 2.5%; anti-Dia, 2.0%; and others. For pregnant patients, anti-D (12.7%) was statistically more frequent. For transfused patients, anti-E (37.3%), anti-c + E (9.5%), anti-C + e (3.3%) and anti-Jka (3.1%) were significantly more frequent.