Endocervical histopathology specimen adequacy in fractional curettage

Abstract

© JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND. Objective: To evaluate the adequacy of endocervical histopathology specimen from fractional curettage (FC) and impact of clinical factors. Materials and Methods: A retrospective descriptive study involving women underwent FCs gathering normal cervical cytology in Ramathibodi Hospital between January 2012 and December 2016. Results: Three hundred eighty-seven participants underwent FC. The indications of FC were 58.4% pre-menopausal abnormal uterine bleeding, 31% post-menopausal bleeding, 10.6% other indications. The overall adequacy of endocervical specimens obtained by endocervical curettage (ECC) was 45.5%, which was higher in pre-menopausal group [48.0% pre-menopause versus 40.9% post-menopause, OR 0.74 (95% CI 0.49 to 1.14)]. There were no statistically significant differences in adequacy of ECC specimens with respect to baseline characteristics. Pathological report of one patient indicated malignancy from both endometrial tissue and ECC (0.2%). The complications rate was 1.3% from procedure and anesthetic complication. Conclusion: ECC provided 45.5% adequacy in women with normal cervical cytology. There was no identified clinical risk factor regarding adequate endocervical specimens.