ความรู้พื้นฐานเกี่ยวกับเซลล์ต้นกำเนิดมีเซนไคม์เพื่อใช้ทางสัตวแพทย์

Abstract

A stem cell is an undifferentiated cell that has special properties for two reasons (1) the ability to increase the number self-renewal and (2) the ability to be differentiated into many cell types, and can be classified into two types (1) embryonic stem cells and (2) adult stem cells. Recent reports found that the differentiated cells can be reprogrammed to embryonic stem-like cells known as induced pluripotent stem cells. In the field of veterinary medicine, much attention has been paid to mesenchymal stem cells (MSCs), one type of adult stem cells. Many reports reveal the success for treating animals; however, there are small number of research have been performed in Thailand. The advantages of using MSCs are it can be easily isolated and cultured, avoiding ethical problems, having little effect on host immune defense, low costs and can be further applied clinically. The limitations of using MSCs are purification, proliferation and differentiation capability. Therefore, a basic science of mesenchymal stem cells is very important for the research question and developments. Thailand should focus on clinical application for build the confidence and enhance the standard of veterinary medicine in Thailand in order to compare with veterinary profession from developed countries, especially innovative new treatment by using mesenchymal stem cells.