Publication:
Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity

Issued Date

2009-07-22

Resource Type

Article

ISSN

18605397
18605397

DOI

10.3762/bjoc.5.36

Other identifier(s)

2-s2.0-75949110371

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Beilstein Journal of Organic Chemistry. Vol.5, (2009)

Suggested Citation

Nisachon Khunnawutmanotham, Nitirat Chimnoi, Arunee Thitithanyanont, Patchreenart Saparpakorn, Kiattawee Choowongkomon, Pornpan Pungpo, Supa Hannongbua, Supanna Techasakul Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity. Beilstein Journal of Organic Chemistry. Vol.5, (2009). doi:10.3762/bjoc.5.36 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/27411

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Title

Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity

Author(s)

Nisachon Khunnawutmanotham
 Nitirat Chimnoi
 Arunee Thitithanyanont
 Patchreenart Saparpakorn
 Kiattawee Choowongkomon
 Pornpan Pungpo
 Supa Hannongbua
 Supanna Techasakul

Other Contributor(s)

Chulabhorn Research Institute
 Mahidol University
 Kasetsart University
 Ubon Rajathanee University

Abstract

Ten dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wildtype and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT. © 2009 Khunnawutmanotham et al; licensee Beilstein-Institut.

Keyword(s)

Chemistry

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/27411

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Scopus 2006-2010