Publication: Omics-based identification of biomarkers for nasopharyngeal carcinoma
Issued Date
2015-01-01
Resource Type
ISSN
18758630
02780240
02780240
Other identifier(s)
2-s2.0-84929377217
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Mahidol University
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SCOPUS
Bibliographic Citation
Disease Markers. Vol.2015, (2015)
Suggested Citation
Tavan Janvilisri Omics-based identification of biomarkers for nasopharyngeal carcinoma. Disease Markers. Vol.2015, (2015). doi:10.1155/2015/762128 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/35521
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Title
Omics-based identification of biomarkers for nasopharyngeal carcinoma
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Abstract
© 2015 Tavan Janvilisri. Nasopharyngeal carcinoma (NPC) is a head and neck cancer that is highly found in distinct geographic areas, such as Southeast Asia. The management of NPC remains burdensome as the prognosis is poor due to the late presentation of the disease and the complex nature of NPC pathogenesis. Therefore, it is necessary to find effective molecular markers for early detection and therapeutic measure of NPC. In this paper, the discovery of molecular biomarker for NPC through the emerging omics technologies including genomics, miRNA-omics, transcriptomics, proteomics, and metabolomics will be extensively reviewed. These markers have been shown to play roles in various cellular pathways in NPC progression. The knowledge on their function will help us understand in more detail the complexity in tumor biology, leading to the better strategies for early detection, outcome prediction, detection of disease recurrence, and therapeutic approach.