Publication: TB outcomes and mortality risk factors in adult migrants at the Thailand-Myanmar border
Issued Date
2020-10-01
Resource Type
ISSN
18157920
Other identifier(s)
2-s2.0-85094935409
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. Vol.24, No.10 (2020), 1009-1015
Suggested Citation
A. Carroll, M. Vincenti-Delmas, B. Maung Maung, W. P.P. Htun, F. Nosten, C. Smith, P. Sonnenberg TB outcomes and mortality risk factors in adult migrants at the Thailand-Myanmar border. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. Vol.24, No.10 (2020), 1009-1015. doi:10.5588/ijtld.20.0014 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/60069
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
TB outcomes and mortality risk factors in adult migrants at the Thailand-Myanmar border
Other Contributor(s)
Abstract
BACKGROUND: Cross-border migrants at the Thailand-Myanmar border are an underserved and vulnerable population. We aimed to identify the causes and risk factors for TB mortality at a migrant-friendly TB programme.METHODS: Routinely collected data on TB cases, treatment outcomes and causes of death were analysed for adult TB cases diagnosed between January 2013 and April 2017. Mortality in the 6 months post-diagnosis was calculated and risk factors were identified using multivariable Poisson regression.RESULTS: Of the 1344 TB cases diagnosed, 1005 started treatment and 128 died. Case fatality rate was 9.5% and the TB mortality rate was 2.4/100 person-months. The number of pre-treatment deaths (33/128) and losses to follow-up (9.0%) were high. Among cases enrolled in treatment, the treatment success rate was 79.8%. When stratified by HIV status, case fatality was higher in HIV-positive cases not on antiretroviral therapy (ART) (90.3%) or with unknown HIV status (31.8%) than those on ART (14.3%) or HIV-negative (8.6%).CONCLUSION: This TB programme achieved high treatment success rates in a population with a substantial burden of TB-HIV coinfection. Expanding access to HIV testing and ART is crucial to reduce mortality. Striving towards same-day TB diagnosis and treatment could reduce death and loss to follow-up.