Publication: Regional patterns in the incidence of aplastic anemia in Thailand
Issued Date
1999-07-08
Resource Type
ISSN
03618609
Other identifier(s)
2-s2.0-0033034221
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
American Journal of Hematology. Vol.61, No.3 (1999), 164-168
Suggested Citation
Surapol Issaragrisil, Paul E. Leaverton, Kanchana Chansung, Tharatorn Thamprasit, Yaowarat Porapakham, Sathit Vannasaeng, Anong Piankijagum, David W. Kaufman, Theresa E. Anderson, Samuel Shapiro, Neal S. Young Regional patterns in the incidence of aplastic anemia in Thailand. American Journal of Hematology. Vol.61, No.3 (1999), 164-168. doi:10.1002/(SICI)1096-8652(199907)61:3<164::AID-AJH2>3.0.CO;2-R Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/25615
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Title
Regional patterns in the incidence of aplastic anemia in Thailand
Abstract
The annual incidence of aplastic anemia has been determined in a rigorous and standardized epidemiologic study conducted in Thailand. A total of 374 cases were identified over a period of 3-6 years in three geographically defined and distinct regions of the country; Bangkok, Khonkaen in the northeast, and Songkla in the south. The incidence was 3.9 cases per million persons in Bangkok, 3.0 per million in Songkla, and 5.0 per million in Khonkaen. These rates are as high or higher than in any region of Europe or Israel as reported in the International Agranulocytosis and Aplastic Anemia Study, in which the methods and case definition were the same. Rates were stable over the course of the study. There were marked differences in incidence between northern and southern rural regions of Thailand, and among Bangkok suburbs. These differences, together with an unusual peak in the incidence among young people in Bangkok, suggest the possibility of occupational and environmental factors in the etiology of aplastic anemia.