Publication: Preparation and characterization of polymeric micelles for disinfectant coating of Catheters
Issued Date
2012-12-01
Resource Type
ISSN
19449380
19449399
19449399
Other identifier(s)
2-s2.0-84875694588
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Proceedings of the IEEE Conference on Nanotechnology. (2012)
Suggested Citation
Hathaichanok Pheungkham, Chayanon Ngambenjawong, Man Theerasilp, Norased Nasongkla Preparation and characterization of polymeric micelles for disinfectant coating of Catheters. Proceedings of the IEEE Conference on Nanotechnology. (2012). doi:10.1109/NANO.2012.6403798 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/13900
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Title
Preparation and characterization of polymeric micelles for disinfectant coating of Catheters
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Abstract
The disinfectant loaded micelle fabrication were investigated as a carrier for 2-benzyl-4-chlorophenol (OBPCP), a disinfectant agent. Micelles were assessed in terms of the drug entrapment efficiency by suitable fabrication process. Results showed that a film sonication method provided the highest drug loading density at 16.35 ± 0.52%. To utilize numerous advantages of these polymer micelles, micelles containing OBPCP were coated on the surface of catheters using Layer-bylayer (LbL) dip coating technique, highlighting the protocol as an improvement in the prolong release of the drug from a period of several hours to several weeks.