Publication: Prevalence and prognosis of myocardial scar in patients with known or suspected coronary artery disease and normal wall motion
Issued Date
2011-12-01
Resource Type
ISSN
1532429X
10976647
10976647
Other identifier(s)
2-s2.0-79955683240
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Cardiovascular Magnetic Resonance. Vol.13, No.1 (2011)
Suggested Citation
Rungroj Krittayaphong, Pairash Saiviroonporn, Thananya Boonyasirinant, Suthipol Udompunturak Prevalence and prognosis of myocardial scar in patients with known or suspected coronary artery disease and normal wall motion. Journal of Cardiovascular Magnetic Resonance. Vol.13, No.1 (2011). doi:10.1186/1532-429X-13-2 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/11937
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Prevalence and prognosis of myocardial scar in patients with known or suspected coronary artery disease and normal wall motion
Other Contributor(s)
Abstract
Background: Some patients may have normal wall motion after myocardial infarction. The aim of this study was to determine the prevalence and prognosis of patients with myocardial scar in the absence of abnormal wall motion. We studied patients with suspected or known coronary artery disease (CAD) who were referred for cardiovascular magnetic resonance (CMR) for the assessment of global and regional cardiac function and late gadolinium enhancement (LGE) and had normal left ventricular wall motion. Prognostic value was determined by the occurrence of hard endpoints (cardiac death and nonfatal myocardial infarction) and major adverse cardiac events (MACE) which also included hospitalization due to unstable angina or heart failure or life threatening ventricular arrhythmia. Results: A total 1148 patients (70.3%) were studied. LGE was detected in 104 patients (9.1%). Prevalence of LGE increased in patients with increased left ventricular mass. Average follow-up time was 955 542 days. LGE was the strongest predictor for hard endpoints and MACE. Conclusion: LGE was detected in 9.1% of patients with suspected or known CAD and normal wall motion. LGE was the strongest predictor of significant cardiac events. © 2011 Krittayaphong et al; licensee BioMed Central Ltd.