Publication:
Cyclic lipodepsipeptides verlamelin A and B, isolated from entomopathogenic fungus Lecanicillium sp.

Issued Date

2014-01-01

Resource Type

Article

ISSN

18811469
00218820

DOI

10.1038/ja.2014.22

Other identifier(s)

2-s2.0-84903537170

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Antibiotics. Vol.67, No.6 (2014), 459-463

Suggested Citation

Kei Ichi Ishidoh, Hiroshi Kinoshita, Yasuhiro Igarashi, Fumio Ihara, Takuya Nihira Cyclic lipodepsipeptides verlamelin A and B, isolated from entomopathogenic fungus Lecanicillium sp.. Journal of Antibiotics. Vol.67, No.6 (2014), 459-463. doi:10.1038/ja.2014.22 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/34916

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Title

Cyclic lipodepsipeptides verlamelin A and B, isolated from entomopathogenic fungus Lecanicillium sp.

Author(s)

Kei Ichi Ishidoh
 Hiroshi Kinoshita
 Yasuhiro Igarashi
 Fumio Ihara
 Takuya Nihira

Other Contributor(s)

Osaka University
 Toyama Prefectural University
 Institute of Fruit Tree and Tea Science, NARO
 Mahidol University

Abstract

Verlamelin and its new derivative (verlamelin B) were isolated from fermentation broth of entomopathogenic fungus Lecanicillium sp. HF627. As the structural elucidation of verlamelin so far was only preliminary, we studied and determined the absolute structure of these two compounds to be cyclo(5S-hydroxytetradecanoic acid-D-alloThr/Ser-D-Ala-L-Pro-L-Gln-D-Tyr-L-Val). This is the first study that precisely analyzed the structure of verlamelin. © 2014 Japan Antibiotics Research Association All rights reserve.

Keyword(s)

Pharmacology, Toxicology and Pharmaceutics

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URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/34916

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