Publication: Coumarins and carbazoles with antiplasmodial activity from Clausena harmandiana
3
Issued Date
2000-05-13
Resource Type
ISSN
00320943
Other identifier(s)
2-s2.0-0034107602
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Planta Medica. Vol.66, No.3 (2000), 277-279
Suggested Citation
Chavi Yenjai, Somkrit Sripontan, Prachack Sriprajun, Prasat Kittakoop, Amnuay Jintasirikul, Morakot Tanticharoen, Yodhathai Thebtaranonth Coumarins and carbazoles with antiplasmodial activity from Clausena harmandiana. Planta Medica. Vol.66, No.3 (2000), 277-279. doi:10.1055/s-2000-8558 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/25798
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Coumarins and carbazoles with antiplasmodial activity from Clausena harmandiana
Abstract
Activity guided fractionation of extracts from Clausena harmandiana have led to the identification of four known compounds, heptaphylline (1), clausine K (2), dentatin (5), and clausarin (6). All these compounds, except clausine K (2), exhibited antiplasmodial activity against Plasmodium falciporum. While the new dimethylated derivative 4, derived from 2, showed no antiplasmodial activity, the monomethylated product 3 (clausine H) exhibited activity comparable to that observed for compounds 1 and 5.