Asian Pacific Journal of Allergy and Immunology. Vol.8, No.1 (1990), 45-58
Suggested Citation
P. Phanichyakarn, C. Kraisarin, C. Sasisakulporn Comparison of inhaled terbutaline and inhaled terbutaline plus ipratropium bromide in acute asthmatic children. Asian Pacific Journal of Allergy and Immunology. Vol.8, No.1 (1990), 45-58. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15964
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Comparison of inhaled terbutaline and inhaled terbutaline plus ipratropium bromide in acute asthmatic children
Twenty asthmatic children, aged 4 to 15 years, consisting of 14 boys and 6 girls, were studied during acute episodes of asthmatic attacks. A group of 10 children each received either inhaled terbutaline 0.5 mg or inhaled terbutaline 0.5 mg followed by ipratropium bromide 0.04 mg 15 minutes later through a 750-ml volumetric spacer. Significant increases in FEV 1 over the baseline were observed from 2 minutes to 2 hours and from 2 minutes to 6 hours following the first and second regimen respectively. A slightly greater increase and longer duration in FEV 1 were observed in the combined drug treatment and very slight decreases in systolic and diastolic blood pressure below the base-line were observed. Neither regimen showed any serious adverse effect on the heart rate and respiratory rate.
