Publication: Anti-inflammatory cyclohexenyl chalcone derivatives in Boesenbergia pandurata
Issued Date
2002-01-31
Resource Type
ISSN
00319422
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2-s2.0-0037203553
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Mahidol University
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SCOPUS
Bibliographic Citation
Phytochemistry. Vol.59, No.2 (2002), 169-173
Suggested Citation
Patoomratana Tuchinda, Vichai Reutrakul, Per Claeson, Ubonwan Pongprayoon, Tuanta Sematong, Thawatchai Santisuk, Walter C. Taylor Anti-inflammatory cyclohexenyl chalcone derivatives in Boesenbergia pandurata. Phytochemistry. Vol.59, No.2 (2002), 169-173. doi:10.1016/S0031-9422(01)00451-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/19994
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Title
Anti-inflammatory cyclohexenyl chalcone derivatives in Boesenbergia pandurata
Abstract
The cyclohexenyl chalcone derivative [(-)-hydroxypanduratin A], together with the previously known panduratin A, sakuranetin, pinostrobin, pinocembrin, and dihydro-5,6-dehydrokawain were isolated from the chloroform extract of the red rhizome variety of Boesenbergia pandurata (Robx.) Schltr. [currently known as Boesenbergia rotunda (L.) Mansf., Kulturpfl.]. Their structures were assigned on the basis of their spectroscopic data. (-)-Hydroxypanduratin A and (-)-panduratin A showed significant topical anti-inflammatory activity in the assay of TPA-induced ear edema in rats. © 2002 Elsevier Science Ltd. All rights reserved.