Publication:
Considerable international variation exists in blood pressure control and antihypertensive prescription patterns in chronic kidney disease

Issued Date

2019-10-01

Resource Type

Article

ISSN

15231755
00852538

DOI

10.1016/j.kint.2019.04.032

Other identifier(s)

2-s2.0-85072224157

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Kidney International. Vol.96, No.4 (2019), 983-994

Suggested Citation

Natalia Alencar de Pinho, Adeera Levin, Masafumi Fukagawa, Wendy E. Hoy, Roberto Pecoits-Filho, Helmut Reichel, Bruce Robinson, Chagriya Kitiyakara, Jinwei Wang, Kai Uwe Eckardt, Vivekanand Jha, Kook Hwan Oh, Laura Sola, Susanne Eder, Martin de Borst, Maarten Taal, Harold I. Feldman, Bénédicte Stengel, Ognjenka Djurdjev, Mila Tang, Naohiki Fujii, Shoichi Maruyama, Takahiro Imaizumi, Jianzhen Zhang, Zaimin Wang, Helen G. Healy, Ziad A. Massy, Christian Combe, Maurice Laville, Roberto Pecoits Filho, Antonio Lopes, Ronald Pisoni, Brian Bieber, Charlotte Tu, Pornpen Sangthawan, Warangkana Pichaiwong, Pinkaew Klyprayong, Paula Orlandi, Raymond Townsend, Alan Go, Luxia Zhang, Vivek Kumar, Ashok Kumar Yadav, Seema Baid-Agrawal, Curie Ahn, Dong Wan Chae, Seung Hyeok Han, Pablo G. Rios, Liliana Gadola, Veronica Lamadrid, Johannes Leierer, Julia Kerschbaum, Martin H. de Borst, Frans J. Van Ittersum, Jan A. Van den Brand, Maarten A. De Jong, Maarten W. Taal, Adam Shardlow Considerable international variation exists in blood pressure control and antihypertensive prescription patterns in chronic kidney disease. Kidney International. Vol.96, No.4 (2019), 983-994. doi:10.1016/j.kint.2019.04.032 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/51407

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Title

Considerable international variation exists in blood pressure control and antihypertensive prescription patterns in chronic kidney disease

Author(s)

Natalia Alencar de Pinho
 Adeera Levin
 Masafumi Fukagawa
 Wendy E. Hoy
 Roberto Pecoits-Filho
 Helmut Reichel
 Bruce Robinson
 Chagriya Kitiyakara
 Jinwei Wang
 Kai Uwe Eckardt
 Vivekanand Jha
 Kook Hwan Oh
 Laura Sola
 Susanne Eder
 Martin de Borst
 Maarten Taal
 Harold I. Feldman
 Bénédicte Stengel
 Ognjenka Djurdjev
 Mila Tang
 Naohiki Fujii
 Shoichi Maruyama
 Takahiro Imaizumi
 Jianzhen Zhang
 Zaimin Wang
 Helen G. Healy
 Ziad A. Massy
 Christian Combe
 Maurice Laville
 Roberto Pecoits Filho
 Antonio Lopes
 Ronald Pisoni
 Brian Bieber
 Charlotte Tu
 Pornpen Sangthawan
 Warangkana Pichaiwong
 Pinkaew Klyprayong
 Paula Orlandi
 Raymond Townsend
 Alan Go
 Luxia Zhang
 Vivek Kumar
 Ashok Kumar Yadav
 Seema Baid-Agrawal
 Curie Ahn
 Dong Wan Chae
 Seung Hyeok Han
 Pablo G. Rios
 Liliana Gadola
 Veronica Lamadrid
 Johannes Leierer
 Julia Kerschbaum
 Martin H. de Borst
 Frans J. Van Ittersum
 Jan A. Van den Brand
 Maarten A. De Jong
 Maarten W. Taal
 Adam Shardlow

Other Contributor(s)

University of Queensland
 Tokai University School of Medicine
 University of New South Wales (UNSW) Australia
 Charité – Universitätsmedizin Berlin
 Université Paris-Sud
 Pontificia Universidade Catolica do Parana
 Faculty of Medicine, Ramathibodi Hospital, Mahidol University
 University of Nottingham
 Peking University
 The University of British Columbia
 Medizinische Universitat Innsbruck
 University of Groningen, University Medical Center Groningen
 University of Pennsylvania Perelman School of Medicine
 Friedrich-Alexander-Universität Erlangen-Nürnberg
 Seoul National University College of Medicine
 Centro de Diálisis Peritoneal
 Arbor Research Collaborative for Health
 Nephrological Center

Abstract

© 2019 International Society of Nephrology Although blood pressure control is a major goal in chronic kidney disease, no worldwide overview of either its achievement or antihypertensive prescriptions is currently available. To evaluate this we compared crude prevalence of uncontrolled blood pressure among 17 cohort studies, including 34 602 individuals with estimated glomerular filtration rate under 60 ml/min/1.73 m2 and treated hypertension across four continents, and estimated observed to expected prevalence ratios, adjusted for potential confounders. Crude prevalence of blood pressure of 140/90 mm Hg or more varied from 28% to 61% and of blood pressure of 130/80 or more from 54% to 84%. Adjusted prevalence ratios indicated poorer hypertension control than expected in cohorts from European countries, India, and Uruguay, and better control in patients from North American and high-income Asian countries. Four antihypertensive drug classes or more were prescribed to more than 30% of participants in North American and some European cohorts, but this practice was less common elsewhere. Renin angiotensin-aldosterone system inhibitors were the most common antihypertensive drugs, prescribed for 54% to 91% of cohort participants. Differences for other drug classes were much stronger, ranging from 11% to 79% for diuretics, 22% to 70% for beta-blockers, and 27% to 75% for calcium-channel blockers. The confounders studied explain only a part of the international variation in blood pressure control among individuals with chronic kidney disease. Thus, considerable heterogeneity in prescription patterns worldwide calls for further investigation into the impact of different approaches on patient outcomes.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/51407

Collections

Scopus 2019