Publication: Physicochemical and osteogenic properties of chairside processed tooth derived bone substitute and bone graft materials
Issued Date
2021-01-01
Resource Type
ISSN
18811361
02874547
02874547
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2-s2.0-85100743374
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Mahidol University
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SCOPUS
Bibliographic Citation
Dental Materials Journal. Vol.40, No.1 (2021), 173-183
Suggested Citation
Khanijou Manop, Zhang Rui, Boonsiriseth Kiatanant, Laovanitch Srisatjaluk Ratchapin, Suphangul Suphachai, Pairuchvej Verasak, Wongsirichat Natthamet, Seriwatanachai Dutmanee Physicochemical and osteogenic properties of chairside processed tooth derived bone substitute and bone graft materials. Dental Materials Journal. Vol.40, No.1 (2021), 173-183. doi:10.4012/dmj.2019-341 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/76835
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Title
Physicochemical and osteogenic properties of chairside processed tooth derived bone substitute and bone graft materials
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Abstract
To analyze physicochemical such as surface structures, the crystallinity, chemical composition, calcium phosphate dissolution and osteogenic properties of tooth derived bone substitute (TDBS) processed chair-side and other grafting materials. The number of anaerobic and facultative anaerobic bacteria in the supernatant of processed TDBS was determined. Human osteoblasts were cocultured with TDBS or allograft in transwell system to examine cell migration. BMP2 released from TDBS was measured by ELISA. TDBS had high crystallinity similar to BoneCeramic while it had a broad pattern to ramus bone, OraGRAFT, and Bio-Oss. TDBS contained carbon, calcium, oxygen, phosphate, sodium and magnesium elements like others. Calcium/phosphorus dissolution of TDBS show closely related to those of mandibular ramus bone and OraGRAFT. In addition, microbial decontamination of TDBS by the chemical processing revealed a hundred percent efficacy. The osteoconductive and osteoinductive properties demonstrated in the TDBS processed chairside suggested the potential of an alternative for bone grafting material.