Publication: Malignant craniopharyngioma; Case report and review of the literature: Case Report
Issued Date
2009-10-01
Resource Type
ISSN
14401789
09196544
09196544
Other identifier(s)
2-s2.0-70349319729
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Mahidol University
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SCOPUS
Bibliographic Citation
Neuropathology. Vol.29, No.5 (2009), 591-596
Suggested Citation
Atthaporn Boongird, Jiraporn Laothamatas, Noppadol Larbcharoensub, Suchart Phudhichareonrat Malignant craniopharyngioma; Case report and review of the literature: Case Report. Neuropathology. Vol.29, No.5 (2009), 591-596. doi:10.1111/j.1440-1789.2008.00986.x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/27908
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Title
Malignant craniopharyngioma; Case report and review of the literature: Case Report
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Abstract
A case of malignant craniopharyngioma in a 46-year-old woman presenting clinically with visual disturbance and bifrontal headache is reported. Histopathologic examination of the suprasellar mass showed a lesion characterized by nests of epithelial cells with a basaloid appearance, round-to-oval nuclei, moderate pleomorphism, hyperchromasia, increased nuclear cytoplastic ratio and high mitotic activity. Immunohistochemically, the tumor cells were positive for Ki-67 (44.3%), p53 (98%), and p63 (100%), but negative for estrogen and progesterone receptors. Clinical and pathologic features with a brief review of the relevant literature for malignant craniopharyngioma as a novel member of tumors of the suprasellar region, is discussed. © 2008 Japanese Society of Neuropathology.