Publication: Frozen autograft-prosthesis composite reconstruction in malignant bone tumors
2
Issued Date
2015-01-01
Resource Type
ISSN
19382367
01477447
01477447
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2-s2.0-84944234472
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Mahidol University
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SCOPUS
Bibliographic Citation
Orthopedics. Vol.38, No.10 (2015), e911-e918
Suggested Citation
Saran Subhadrabandhu, Akihiko Takeuchi, Norio Yamamoto, Toshiharu Shirai, Hideji Nishida, Katsuhiro Hayashi, Shinji Miwa, Hiroyuki Tsuchiya Frozen autograft-prosthesis composite reconstruction in malignant bone tumors. Orthopedics. Vol.38, No.10 (2015), e911-e918. doi:10.3928/01477447-20151002-59 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/36825
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Title
Frozen autograft-prosthesis composite reconstruction in malignant bone tumors
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Abstract
Copyright © SLACK Incorporated. Several methods are available using an endoprosthesis or biological reconstruction for malignant bone tumors. Methods that use allograft-prosthesis composites have shown promising results. In 1999, the authors developed a method of reconstruction that uses a tumor-bearing autograft treated with liquid nitrogen. This technique was modified to produce a pedicle frozen autograft to maintain anatomical continuity on one side. In this study, the results of bone reconstructions using frozen autograftprosthesis composites were retrospectively evaluated. The demographic data, histological records, surgical procedures, functional scores, and complications of 22 patients who had bone sarcoma or metastasis and at least 2 years of follow-up were reviewed. There were 19 patients with primary bone sarcoma and 3 with bone metastasis. Average age was 36 years (range, 9-73 years), and mean follow-up was 63 months (range, 24-176 months). Reconstructions were performed on 10 proximal femurs, 5 distal femurs, 4 proximal tibias, 1 proximal humerus, 1 proximal radius, and 1 hemipelvis. There were 12 pedicle-freezing and 10 free-freezing procedures. Union rate was 90% (9/10), and average union time was 9.5 months. Average Musculoskeletal Tumor Society score was 89.3%. Complications included 1 fracture, 2 infections, 3 soft tissue recurrences, and 1 posterior interosseous nerve palsy. The authors concluded that the frozen autograft-prosthesis composite demonstrated excellent Musculoskeletal Tumor Society scores, a low complication rate, and a good union rate and was superior when used with the pedicle-freezing technique.