Publication: Valacyclovir for herpes simplex encephalitis
| dc.contributor.author | Thomas Pouplin | en_US |
| dc.contributor.author | Julie Nguyen Pouplin | en_US |
| dc.contributor.author | Pham Van Toi | en_US |
| dc.contributor.author | Niklas Lindegardh | en_US |
| dc.contributor.author | H. Rogier Van Doorn | en_US |
| dc.contributor.author | Tran Tinh Hien | en_US |
| dc.contributor.author | Jeremy Farrar | en_US |
| dc.contributor.author | M. Estée Török | en_US |
| dc.contributor.author | Tran Thi Hong Chau | en_US |
| dc.contributor.other | UCL | en_US |
| dc.contributor.other | Cambridge University Hospitals NHS Foundation Trust | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-05-03T08:29:55Z | |
| dc.date.available | 2018-05-03T08:29:55Z | |
| dc.date.issued | 2011-07-01 | en_US |
| dc.description.abstract | The recommended treatment for herpes simplex encephalitis (HSE) remains intravenous acyclovir. In resource-poor countries, however, intravenous formulations are usually unavailable or unaffordable. We report the penetration of acyclovir into the cerebrospinal fluid (CSF) in patients with HSE, treated with the oral prodrug valacyclovir at 1,000 mg three times daily. The oral therapy achieved adequate acyclovir concentrations in the CSF and may be an acceptable early treatment for suspected HSE in resource-limited settings. Copyright © 2011, American Society for Microbiology. All Rights Reserved. | en_US |
| dc.identifier.citation | Antimicrobial Agents and Chemotherapy. Vol.55, No.7 (2011), 3624-3626 | en_US |
| dc.identifier.doi | 10.1128/AAC.01023-10 | en_US |
| dc.identifier.issn | 10986596 | en_US |
| dc.identifier.issn | 00664804 | en_US |
| dc.identifier.other | 2-s2.0-79959249152 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/12451 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79959249152&origin=inward | en_US |
| dc.subject | Medicine | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Valacyclovir for herpes simplex encephalitis | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79959249152&origin=inward | en_US |