Publication: Reticulocyte analysis in systemic lupus erythematosus and chronic renal failure using flow cytometry
Issued Date
2000-03-01
Resource Type
ISSN
0125877X
Other identifier(s)
2-s2.0-0033949427
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Mahidol University
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SCOPUS
Bibliographic Citation
Asian Pacific Journal of Allergy and Immunology. Vol.18, No.1 (2000), 23-27
Suggested Citation
Punnee Butthep, Sumalee Jindadamrongwech, Preyarat Kaewkethong, Boonreun Panyayutho, Raewadee Wisedpanichkij, Ahnond Bunyaratvej Reticulocyte analysis in systemic lupus erythematosus and chronic renal failure using flow cytometry. Asian Pacific Journal of Allergy and Immunology. Vol.18, No.1 (2000), 23-27. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/25990
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Title
Reticulocyte analysis in systemic lupus erythematosus and chronic renal failure using flow cytometry
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Abstract
The number and maturation of circulating reticulocytes were measured in patients with systemic lupus erythematosus (SLE) and chronic renal failure (CRF) using an automated hematological analyzer (Technicon H*3 RTX) for their erythropoietic activities. Both SLE and CRF patients had increased reticulocyte numbers with a low degree of maturation. The SLE patients had no changes in mean reticulocyte corpuscular volume (MCVr) as compared to normal subjects (110.20 ± 15.43 fl. in SLE and 110.39 ± 5.09 fl. in normal), whereas CRF patients had significantly increased mean corpuscular reticulocyte volume (MCVr = 120.99 ± 8.09 fl., p-value = 0.0019 as compared with normal). Three cases of SLE with nephrotic syndrome (NS) had high degree of MCVr (113.4, 125.0 and 133.1 fl., respectively). The renal involvement in SLE patients and CRF patients may associate with increased reticulocyte corpuscular volume.