Publication: HPLC quantitative analysis of rhein and antidermatophytic activity of cassia fistula pod pulp extracts of various storage conditions
Issued Date
2013-10-21
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ISSN
23146141
23146133
23146133
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2-s2.0-84885596218
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Mahidol University
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SCOPUS
Bibliographic Citation
BioMed Research International. Vol.2013, (2013)
Suggested Citation
Savita Chewchinda, Mansuang Wuthi-Udomlert, Wandee Gritsanapan HPLC quantitative analysis of rhein and antidermatophytic activity of cassia fistula pod pulp extracts of various storage conditions. BioMed Research International. Vol.2013, (2013). doi:10.1155/2013/821295 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/31186
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Title
HPLC quantitative analysis of rhein and antidermatophytic activity of cassia fistula pod pulp extracts of various storage conditions
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Abstract
Cassia fistula is well known for its laxative and antifungal properties due to anthraquinone compounds in the pods. This study quantitatively analyzed rhein in the C. fistula pod pulp decoction extracts kept under various storage conditions using HPLC. The antifungal activity of the extracts and their hydrolyzed mixture was also evaluated against dermatophytes. The contents of rhein in all stored decoction extracts remained more than 95% (95.69-100.66%) of the initial amount (0.0823 ± 0.001 % w/w). There was no significant change of the extracts kept in glass vials and in aluminum foil bags. The decoction extract of C. fistula pod pulp and its hydrolyzed mixture containing anthraquinone aglycones were tested against clinical strains of dermatophytes by broth microdilution technique. The results revealed good chemical and antifungal stabilities against dermatophytes of C. fistula pod pulp decoction extracts stored under various accelerated and real time storage conditions. © 2013 Savita Chewchinda et al.
