Publication: Primary cardiac angiosarcoma with systemic metastases; a case report and review of the literature
Issued Date
2004-09-01
Resource Type
ISSN
01252208
Other identifier(s)
2-s2.0-5444238653
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.87, No.9 (2004), 1116-1122
Suggested Citation
Noppadol Larbcharoensub, Arunee Singhsnaeh, Paisan Leelachaikul Primary cardiac angiosarcoma with systemic metastases; a case report and review of the literature. Journal of the Medical Association of Thailand. Vol.87, No.9 (2004), 1116-1122. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/21556
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Title
Primary cardiac angiosarcoma with systemic metastases; a case report and review of the literature
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Abstract
Angiosarcoma is a relatively uncommon primary malignant tumor of the heart derived from the endothelial cells. The authors report a case of primary cardiac angiosarcoma of the right atrium with pulmonary, hepatic, cerebellar and bony metastases in a 46-year-old man who clinically presented as pulmonary hemorrhage. The patient's occupational history had occasional exposure to polyvinyl chloride. The autopsy examination of the cardiac angiosarcoma characterized macroscopically by a right atrial tumor and histologically by anastomosing vascular channels and minute atypical pleomorphic endothelial cells. Immunohistological stainings were positive CD31, CD34 and focal positive factor VIII-related antigen. Clinical and pathologic features with briefly reviewed relevant literatures are discussed. This is the first reported description in the literature of a primary cardiac angiosarcoma with systemic metastases to multiple organs in Thailand.