Publication: Climate induces seasonality in pneumococcal transmission.
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Accepted Date
2015-05-21
Issued Date
2015-06
Resource Type
Language
eng
ISSN
2045-2322 (electronic)
Rights
Mahidol University
Rights Holder(s)
Scientific reports
Bibliographic Citation
Numminen E, Chewapreecha C, Turner C, Goldblatt D, Nosten F, Bentley SD, et al. Climate induces seasonality in pneumococcal transmission. Sci Rep. 2015 Jun 12;5:11344.
Suggested Citation
Numminen, Elina, Chewapreecha, Claire, Turner, Claudia, Goldblatt, David, Nosten, Francois, Bentley, Stephen D., Turner, Paul, Corander, Jukka Climate induces seasonality in pneumococcal transmission.. Numminen E, Chewapreecha C, Turner C, Goldblatt D, Nosten F, Bentley SD, et al. Climate induces seasonality in pneumococcal transmission. Sci Rep. 2015 Jun 12;5:11344.. doi:10.1038/srep11344. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/802
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Title
Climate induces seasonality in pneumococcal transmission.
Corresponding Author(s)
Abstract
Streptococcus pneumoniae is a significant human pathogen and a leading cause of
infant mortality in developing countries. Considerable global variation in the
pneumococcal carriage prevalence has been observed and the ecological factors
contributing to it are not yet fully understood. We use data from a cohort of
infants in Asia to study the effects of climatic conditions on both acquisition
and clearance rates of the bacterium, finding significantly higher
transmissibility during the cooler and drier months. Conversely, the length of a
colonization period is unaffected by the season. Independent carriage data from
studies conducted on the African and North American continents suggest similar
effects of the climate on the prevalence of this bacterium, which further
validates the obtained results. Further studies could be important to replicate
the findings and explain the mechanistic role of cooler and dry air in the
physiological response to nasopharyngeal acquisition of the pneumococcus.