Publication: Pedal bypass with deep venous arterialization: The therapeutic option in critical limb ischemia and unreconstructable distal arteries
Issued Date
2011-12-01
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ISSN
17085381
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2-s2.0-84858985829
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Mahidol University
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SCOPUS
Bibliographic Citation
Vascular. Vol.19, No.6 (2011), 313-319
Suggested Citation
Pramook Mutirangura, Chanean Ruangsetakit, Chumpol Wongwanit, Nuttawut Sermsathanasawadi, Khamin Chinsakchai Pedal bypass with deep venous arterialization: The therapeutic option in critical limb ischemia and unreconstructable distal arteries. Vascular. Vol.19, No.6 (2011), 313-319. doi:10.1258/vasc.2010.oa0278 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/12163
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Title
Pedal bypass with deep venous arterialization: The therapeutic option in critical limb ischemia and unreconstructable distal arteries
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Abstract
Heavily calcified and severely stenotic distal arteries defined as unreconstructable, precludes the possibility of revascularization, resulting in major amputation in patients with critical limb ischemia. However, providing blood supply to the ischemic foot through the venous system instead of the arterial system may improve the circulation adequately for the healing process in the vascular compromised distal tissue. This study aimed to assess the safety and efficacy of pedal bypass with deep venous arterialization, one of the possible procedures to improve the circulation through the venous system in critically ischemic limbs and unreconstructable distal arteries. Twenty-six patients with critical limb ischemia and an unreconstructable distal artery of the lower extremities were included for the surgical procedure. Arterial bypass with distal anastomosis at the paramalleolar deep vein was carried out through a composite graft combined with adequate destruction of valve competency in the distal vein. The primary endpoint was complete healing of ischemic ulcer with amelioration of rest pain within six months. The secondary endpoints were the outcomes of survival, limb salvage and primary graft patency rate at six-month intervals to 24 months. Nineteen patients (73.1%) had complete healing of ischemic ulcer and disappearance of rest pain within six months. Six patients (23.1%) underwent major amputation. Perioperative mortality was 3.8%. After 24 months of follow-up study, the survival rate was 87.5%, whereas the limb salvage and graft patency rates were 76.02 and 49.17%, respectively. Pedal bypass with deep venous arterialization may be another therapeutic option to enhance the healing of ischemic ulcer and limb salvageability in patients with critical limb ischemia and unreconstructable distal artery. © 2011 Royal Society of Medicine Press. All rights reserved.