Publication:
Efavirenz 600 mg/day versus efavirenz 800 mg/day in HIV-infected patients with tuberculosis receiving rifampicin: 48 Weeks results

1

Issued Date

2006-01-01

Resource Type

Article

ISSN

02699370

DOI

10.1097/01.aids.0000196181.18916.9b

Other identifier(s)

2-s2.0-29144458259

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

AIDS. Vol.20, No.1 (2006), 131-132

Suggested Citation

Weerawat Manosuthi, Sasisopin Kiertiburanakul, Somnuek Sungkanuparph, Kiat Ruxrungtham, Asda Vibhagool, Sasivimol Rattanasiri, Ammarin Thakkinstian Efavirenz 600 mg/day versus efavirenz 800 mg/day in HIV-infected patients with tuberculosis receiving rifampicin: 48 Weeks results. AIDS. Vol.20, No.1 (2006), 131-132. doi:10.1097/01.aids.0000196181.18916.9b Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/23378

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Title

Efavirenz 600 mg/day versus efavirenz 800 mg/day in HIV-infected patients with tuberculosis receiving rifampicin: 48 Weeks results

Author(s)

Weerawat Manosuthi
 Sasisopin Kiertiburanakul
 Somnuek Sungkanuparph
 Kiat Ruxrungtham
 Asda Vibhagool
 Sasivimol Rattanasiri
 Ammarin Thakkinstian

Other Contributor(s)

Bamrasnaradura Infectious Disease Institute
 Mahidol University
 The HIV Netherlands Australia Thailand Research Collaboration

Abstract

The potential of drug-drug interaction between efavirenz and rifampicin is a major concern in the treatment of HIV and tuberculosis. The optimal efavirenz dosage is still unclear. Our randomized control trial study recently reported the similar efavirenz level between efavirenz 600 and 800 mg/day in HIV-infected patients receiving rifampicin. We report the similar virological and immunological outcomes at 48 weeks between the two groups. Efavirenz 600 mg/day should be sufficient for concurrent use with rifamipicin.

Keyword(s)

Immunology and Microbiology
 Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/23378

Collections

Scopus 2006-2010