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Epidemiological and Molecular Characterization of Dengue Virus Circulating in Bhutan, 2013-2014

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dc.contributor.authorSangay Zangmoen_US
dc.contributor.authorChonticha Klungthongen_US
dc.contributor.authorPiyawan Chinnawirotpisanen_US
dc.contributor.authorSrisurang Tantimavanichen_US
dc.contributor.authorNathamon Kosoltanapiwaten_US
dc.contributor.authorButsaya Thaisomboonsuken_US
dc.contributor.authorKelzang Phuntshoen_US
dc.contributor.authorSonam Wangchuken_US
dc.contributor.authorIn-Kyu Yoonen_US
dc.contributor.authorStefan Fernandezen_US
dc.contributor.otherMahidol University. Faculty of Medical Technology. Department of Clinical Microbiology and Applied Technologyen_US
dc.date.accessioned2015-09-28T03:48:32Z
dc.date.accessioned2017-06-20T16:43:09Z
dc.date.available2015-09-28T03:48:32Z
dc.date.available2017-06-20T16:43:09Z
dc.date.issued2015-08-21
dc.description.abstractDengue is one of the most significant public health problems in tropical and subtropical countries, and is increasingly being detected in traditionally non-endemic areas. In Bhutan, dengue virus (DENV) has only recently been detected and limited information is available. In this study, we analyzed the epidemiological and molecular characteristics of DENV in two southern districts in Bhutan from 2013–2014. During this period, 379 patients were clinically diagnosed with suspected dengue, of whom 119 (31.4%) were positive for DENV infection by NS1 ELISA and/or nested RT-PCR. DENV serotypes 1, 2 and 3 were detected with DENV-1 being predominant. Phylogenetic analysis of DENV-1 using envelope gene demonstrated genotype V, closely related to strains from northern India.en_US
dc.identifier.citationPlos Neglected Tropical Diseases. Vol.9, No.8 (2015), 1-14en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/2124
dc.language.isoengen_US
dc.subjectOpen Access articleen_US
dc.titleEpidemiological and Molecular Characterization of Dengue Virus Circulating in Bhutan, 2013-2014en_US
dc.typeArticleen_US
dspace.entity.typePublication
mods.location.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546418/

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