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Antiserum to the gp116 glycoprotein of yellow head virus neutralizes infectivity in primary lymphoid organ cells of Penaeus monodon

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dc.contributor.authorWanchai Assavalapsakulen_US
dc.contributor.authorWitoon Tirasophonen_US
dc.contributor.authorSakol Panyimen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-06-21T08:06:56Z
dc.date.available2018-06-21T08:06:56Z
dc.date.issued2005-01-25en_US
dc.description.abstractYellow head virus (YHV) is an invertebrate nidovirus that has caused mass mortality of cultured Penaeus monodon in Asia. In this study, we investigated whether mouse polyclonal anti-serum raised against the YHV gp116 or gp64 structural glycoproteins could neutralize YHV infectivity as determined using an in vitro quantal assay in primary cultures of lymphoid organ cells. Anti-gp116 antiserum showed virus-neutralizing activity whereas anti-gp64 antiserum failed to inhibit infection. The results suggest that gp116 antiserum blocks binding of virions to cellular receptors to facilitate YHV entry into lymphoid organ cells.en_US
dc.identifier.citationDiseases of Aquatic Organisms. Vol.63, No.1 (2005), 85-88en_US
dc.identifier.doi10.3354/dao063085en_US
dc.identifier.issn01775103en_US
dc.identifier.other2-s2.0-13944266022en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/16233
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=13944266022&origin=inwarden_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.titleAntiserum to the gp116 glycoprotein of yellow head virus neutralizes infectivity in primary lymphoid organ cells of Penaeus monodonen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=13944266022&origin=inwarden_US

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