Publication:
Successful treatment of acquired amegakaryocytic thrombocytopenic purpura refractory to corticosteroids and intravenous immunoglobulin with antithymocyte globulin and cyclosporin

Issued Date

2008-09-01

Resource Type

Article

ISSN

09255710

DOI

10.1007/s12185-008-0125-0

Other identifier(s)

2-s2.0-56649089766

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

International Journal of Hematology. Vol.88, No.2 (2008), 223-226

Suggested Citation

Pimjai Niparuck, Vichai Atichartakarn, Suporn Chuncharunee Successful treatment of acquired amegakaryocytic thrombocytopenic purpura refractory to corticosteroids and intravenous immunoglobulin with antithymocyte globulin and cyclosporin. International Journal of Hematology. Vol.88, No.2 (2008), 223-226. doi:10.1007/s12185-008-0125-0 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/19552

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Title

Successful treatment of acquired amegakaryocytic thrombocytopenic purpura refractory to corticosteroids and intravenous immunoglobulin with antithymocyte globulin and cyclosporin

Author(s)

Pimjai Niparuck
 Vichai Atichartakarn
 Suporn Chuncharunee

Other Contributor(s)

Mahidol University

Abstract

Four patients with acquired amegakaryocytic thrombocytopenic purpura, who had failed corticosteroids, intravenous immunoglobulin and cyclophosphamide therapy, were treated with antithymocyte globulin, followed by cyclosporin. Three patients achieved complete remission in 28-178 days and the response duration was 16-60 months from the beginning of treatment. One patient achieved a partial response for 2 months followed by myelodysplastic syndrome 5 months later. He died in 9 months due to intracerebral bleeding. Marrow cytogenetics showed 47, XY, +21. © 2008 The Japanese Society of Hematology.

Keyword(s)

Medicine

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URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/19552

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