Publication:
Increased phagocytosis of Plasmodium falciparum-infected erythrocytes with haemoglobin E by peripheral blood monocytes

Issued Date

1986-01-01

Resource Type

Article

ISSN

14219662
00015792

DOI

10.1159/000206041

Other identifier(s)

2-s2.0-0022914687

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Acta Haematologica. Vol.76, No.2-3 (1986), 155-158

Suggested Citation

Ahnond Bunyaratvej, Punnee Butthep, Yongyuth Yuthavong, Suthat Fucharoen, Srisin Khusmith, Sutee Yoksan, Prawase Wasi Increased phagocytosis of Plasmodium falciparum-infected erythrocytes with haemoglobin E by peripheral blood monocytes. Acta Haematologica. Vol.76, No.2-3 (1986), 155-158. doi:10.1159/000206041 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/9854

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Title

Increased phagocytosis of Plasmodium falciparum-infected erythrocytes with haemoglobin E by peripheral blood monocytes

Author(s)

Ahnond Bunyaratvej
 Punnee Butthep
 Yongyuth Yuthavong
 Suthat Fucharoen
 Srisin Khusmith
 Sutee Yoksan
 Prawase Wasi

Other Contributor(s)

Faculty of Medicine, Ramathibodi Hospital, Mahidol University
 Faculty of Science
 Faculty of Medicine, Siriraj Hospital, Mahidol University
 Mahidol University

Abstract

Erythrocytes from subjects with homozygous and heterozygous haemoglobin E (HbE) infected with Plasmodium falciparum in vitro were phagocytosed to a greater extent by normal human monocytes than infected erythrocytes from normal subjects. Susceptibility to phagocytosis was maximal when the parasites developed to trophozoite and schizont stages in both normal and patients' erythrocytes. The increased susceptibility of P. falciparum-infected HbE erythrocytes to phagocytosis by monocytes may play a role in protection against malaria. © 1986 S. Karger AG, Basel.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/9854

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Scopus 1969-1990