Publication: An update on mosquito cell expressed dengue virus receptor proteins
Issued Date
2012-02-01
Resource Type
ISSN
13652583
09621075
09621075
Other identifier(s)
2-s2.0-84855925693
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Insect Molecular Biology. Vol.21, No.1 (2012), 1-7
Suggested Citation
D. R. Smith An update on mosquito cell expressed dengue virus receptor proteins. Insect Molecular Biology. Vol.21, No.1 (2012), 1-7. doi:10.1111/j.1365-2583.2011.01098.x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/13501
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
An update on mosquito cell expressed dengue virus receptor proteins
Author(s)
Other Contributor(s)
Abstract
Dengue is the most important mosquito transmitted viral disease of humans worldwide. Despite intensive study over several decades, many of the fine details of the dengue virus (DENV) replication cycle remain unknown, although generally more is known about the phase of the replication cycle in mammalian cells as compared to the phase in mosquito cells. This results from a combination of less research emphasis on the mosquito stage, as well as fewer tools such as specific antibodies against mosquito proteins and insect informatics databases. The binding of a virus to a host cell is a first and critical stage in the infectious process and the mechanism and identity of cellular proteins involved in this process remains largely unknown. This short review aims to provide an update on our current understanding of the proteins expressed by mosquito cells that mediate DENV binding as a prerequisite to DENV entry and replication. © 2011 The Royal Entomological Society.