Publication: Efficacy and safety of 308-nm excimer lamp in the treatment of scalp psoriasis: a retrospective study
Issued Date
2019-05-01
Resource Type
ISSN
16000781
09054383
09054383
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2-s2.0-85060857404
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Mahidol University
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SCOPUS
Bibliographic Citation
Photodermatology Photoimmunology and Photomedicine. Vol.35, No.3 (2019), 172-177
Suggested Citation
Ploysyne Rattanakaemakorn, Phanitchanat Phusuphitchayanan, Kallapan Pakornphadungsit, Kunlawat Thadanipon, Poonkiat Suchonwanit Efficacy and safety of 308-nm excimer lamp in the treatment of scalp psoriasis: a retrospective study. Photodermatology Photoimmunology and Photomedicine. Vol.35, No.3 (2019), 172-177. doi:10.1111/phpp.12448 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/51068
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Title
Efficacy and safety of 308-nm excimer lamp in the treatment of scalp psoriasis: a retrospective study
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Abstract
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Background: Scalp psoriasis is a major therapeutic challenge due to the hindrance caused by hair. Treatment with the 308-nm excimer lamp is purported to provide many benefits over conventional phototherapy. This retrospective study evaluates the efficacy, safety, and effective dosage of 308-nm excimer light in the treatment of scalp psoriasis. Methods: We retrospectively reviewed the medical records of patients with scalp psoriasis who received treatment with 308-nm excimer light. Clinical and epidemiological data as well as details regarding treatment were statistically analyzed to determine the treatment outcomes. Results: Twenty patients with scalp psoriasis were included in the study. Their mean age was 47.45 ± 17.93 years. Eleven patients responded to treatment at the end of 10 sessions. The median baseline Psoriatic Scalp Severity Index (PSSI) was 12 (range, 3-32). At the end of the protocol, the median PSSI was 4.5 (range, 0-24), indicating a statistically significant reduction (P < 0.001). Common adverse effects included erythema, irritation, and desquamation. Conclusion: The 308-nm excimer light appears to be an effective and safe modality that requires short treatment time. The modality could be considered as an alternative or adjuvant treatment for scalp psoriasis.