Publication: Successful medical treatment of multiple cryptococcomas : Report of a case and literature review
Issued Date
1999-10-01
Resource Type
ISSN
01252208
Other identifier(s)
2-s2.0-0032777293
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.82, No.10 (1999), 990-999
Suggested Citation
Arkhom Arayawichanont, Naraporn Prayoonwiwat, Anchalee Churojana, Tumtip Sangruchi, Niphon Poungvarin Successful medical treatment of multiple cryptococcomas : Report of a case and literature review. Journal of the Medical Association of Thailand. Vol.82, No.10 (1999), 990-999. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/25575
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Title
Successful medical treatment of multiple cryptococcomas : Report of a case and literature review
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Abstract
We report a 35 year old man diagnosed as having CNS cryptococcosis with multiple cryptococcomas, presenting with headache, papilloedema and impaired mental function in a previously healthy man. Cerebrospinal fluid (CSF) examination revealed lymphocytic pleocytosis with low glucose level. Gram's stain, acid fast bacilli stain and Indian ink examination were all negative. CSF cryptococcal antigen was positive, however, several fungal cultures were negative. Early cranial CT scan showed focal cerebritis over the right temporal lobe while subsequent imaging studies showed multiple contrast-enhancing masses with severe surrounding brain oedema over bilateral frontoparietal areas. Brain biopsy showed cryptococcal granulomatous lesions. Treatment was successful with antifungal agents and steroids without surgical removal.