Publication:
Thermodynamic study on the gas chromatographic separation of the enantiomers of aromatic alcohols using heptakis(2,3-di-O-methyl-6-O-tert- butyldimethylsilyl)-β-cyclodextrin as a stationary phase

Issued Date

2004-09-17

Resource Type

Article

ISSN

00219673

DOI

10.1016/j.chroma.2004.08.022

Other identifier(s)

2-s2.0-4444370795

Rights

Mahidol University

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SCOPUS

Bibliographic Citation

Journal of Chromatography A. Vol.1049, No.1-2 (2004), 223-226

Suggested Citation

Aroonsiri Shitangkoon, Jirawit Yanchinda, Juwadee Shiowatana Thermodynamic study on the gas chromatographic separation of the enantiomers of aromatic alcohols using heptakis(2,3-di-O-methyl-6-O-tert- butyldimethylsilyl)-β-cyclodextrin as a stationary phase. Journal of Chromatography A. Vol.1049, No.1-2 (2004), 223-226. doi:10.1016/j.chroma.2004.08.022 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/21150

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Title

Thermodynamic study on the gas chromatographic separation of the enantiomers of aromatic alcohols using heptakis(2,3-di-O-methyl-6-O-tert- butyldimethylsilyl)-β-cyclodextrin as a stationary phase

Author(s)

Aroonsiri Shitangkoon
 Jirawit Yanchinda
 Juwadee Shiowatana

Other Contributor(s)

Chulalongkorn University
 Mahidol University

Abstract

Gas chromatographic separation of the enantiomers of nineteen structurally related aromatic alcohols was investigated as a function of temperature using a heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin- coated capillary column. Thermodynamic parameters were determined and compared with those obtained with the nonchiral, reference stationary phase, OV-1701. While the -ΔH and -ΔS values for the more retained enantiomers of all nineteen alcohols are comparable on the chiral stationary phase used, the -Δ(ΔH) and -Δ(ΔS) values are considerably different. Of all the solutes tested, enantiodiscrimination was the greatest for the 2,6-difluoro-α-methylbenzyl alcohol. © 2004 Elsevier B.V. All rights reserved.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/21150

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Scopus 2001-2005