Publication: Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: A case report
Issued Date
2021-02-01
Resource Type
ISSN
1875855X
19057415
19057415
Other identifier(s)
2-s2.0-85101560034
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Mahidol University
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SCOPUS
Bibliographic Citation
Asian Biomedicine. Vol.15, No.1 (2021), 43-48
Suggested Citation
Supat Chamnanchanunt, Pravinwan Thungthong, Chajchawan Nakhakes, Putza Chonsawat, Tawatchai Suwanban Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: A case report. Asian Biomedicine. Vol.15, No.1 (2021), 43-48. doi:10.1515/abm-2021-0006 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/76287
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Title
Atypical complication in an adult patient with dengue and autoimmune hemolytic anemia: A case report
Abstract
Severe dengue infection is associated with life-threatening complications, including severe bleeding. The bleeding tendency is typically associated with the shock phase of infection, for which blood replacement may be needed. However, repetitive blood transfusion can lead to volume overload. Administration of recombinant activated factor VII (rFVIIa) might be used to counteract bleeding without inducing volume overload. We describe the case of a patient with severe dengue infection who presented with intractable bleeding; he was initially treated with massive blood transfusions, which resulted in volume overload. He was then treated with rFVIIa to reverse the bleeding. During the second week of his hospitalization, his hematocrit dropped precipitously, and autoimmune hemolytic anemia was diagnosed. Supportive treatment was provided until recovery. Autoimmune hemolytic anemia is a rare complication in adult patients with dengue. Supportive care was effective for this atypical complication.