Publication: Detecting prediabetes and diabetes: Agreement between fasting plasma glucose and oral glucose tolerance test in Thai adults
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Issued Date
2015-01-01
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ISSN
23146753
23146745
23146745
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2-s2.0-84939632261
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Diabetes Research. Vol.2015, (2015)
Suggested Citation
Wichai Aekplakorn, Valla Tantayotai, Sakawduan Numsangkul, Wilarwan Sripho, Nutchanat Tatsato, Tuanjai Burapasiriwat, Rachada Pipatsart, Premsuree Sansom, Pranee Luckanajantachote, Pongpat Chawarokorn, Anek Thanonghan, Watchira Lakhamkaew, Aungsumalin Mungkung, Rungnapa Boonkean, Chanidsa Chantapoon, Mayuree Kungsri, Kasetsak Luanseng, Kornsinun Chaiyajit Detecting prediabetes and diabetes: Agreement between fasting plasma glucose and oral glucose tolerance test in Thai adults. Journal of Diabetes Research. Vol.2015, (2015). doi:10.1155/2015/396505 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/35629
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Title
Detecting prediabetes and diabetes: Agreement between fasting plasma glucose and oral glucose tolerance test in Thai adults
Author(s)
Wichai Aekplakorn
Valla Tantayotai
Sakawduan Numsangkul
Wilarwan Sripho
Nutchanat Tatsato
Tuanjai Burapasiriwat
Rachada Pipatsart
Premsuree Sansom
Pranee Luckanajantachote
Pongpat Chawarokorn
Anek Thanonghan
Watchira Lakhamkaew
Aungsumalin Mungkung
Rungnapa Boonkean
Chanidsa Chantapoon
Mayuree Kungsri
Kasetsak Luanseng
Kornsinun Chaiyajit
Valla Tantayotai
Sakawduan Numsangkul
Wilarwan Sripho
Nutchanat Tatsato
Tuanjai Burapasiriwat
Rachada Pipatsart
Premsuree Sansom
Pranee Luckanajantachote
Pongpat Chawarokorn
Anek Thanonghan
Watchira Lakhamkaew
Aungsumalin Mungkung
Rungnapa Boonkean
Chanidsa Chantapoon
Mayuree Kungsri
Kasetsak Luanseng
Kornsinun Chaiyajit
Abstract
© 2015 Wichai Aekplakorn et al. Aim. To evaluate an agreement in identifying dysglycemia between fasting plasma glucose (FPG) and the 2 hr postprandial glucose tolerance test (OGTT) in a population with high risk of diabetes. Methods. A total of 6,884 individuals aged 35-65 years recruited for a community-based diabetes prevention program were tested for prediabetes including impaired fasting glucose (IFG) or impaired glucose tolerance (IGT), and diabetes. The agreement was assessed by Kappa statistics. Logistic regression was used to examine factors associated with missed prediabetes and diabetes by FPG. Results. A total of 2671 (38.8%) individuals with prediabetes were identified. The prevalence of prediabetes identified by FPG and OGTT was 32.2% and 22.3%, respectively. The proportions of diabetes classified by OGTT were two times higher than those identified by FPG (11.0% versus 5.4%, resp.). The Kappa statistics for agreement of both tests was 0.55. Overall, FPG missed 46.3% of all prediabetes and 54.7% of all diabetes cases. Prediabetes was more likely to be missed by FPG among female, people aged <45 yrs, and those without family history of diabetes. Conclusion. The detection of prediabetes and diabetes using FPG only may miss half of the cases. Benefit of adding OGTT to FPG in some specific groups should be confirmed.