Publication: In vivo assessments to detect antimalarial resistance
2
Issued Date
2019-01-01
Resource Type
ISSN
19406029
10643745
10643745
Other identifier(s)
2-s2.0-85068860531
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Methods in Molecular Biology. Vol.2013, (2019), 105-121
Suggested Citation
Mehul J. Dhorda, Arjen M. Dondorp In vivo assessments to detect antimalarial resistance. Methods in Molecular Biology. Vol.2013, (2019), 105-121. doi:10.1007/978-1-4939-9550-9_8 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/50363
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
In vivo assessments to detect antimalarial resistance
Author(s)
Other Contributor(s)
Abstract
© Springer Science+Business Media, LLC, part of Springer Nature 2019. In vivo drug clinical trials are the gold standard for assessing the therapeutic efficacy of antimalarials. They must be conducted in a rigorous and standardized manner so that the resistance of antimalarial drugs can be compared both in time and in space. This chapter presents the methodology for conducting such clinical studies of antimalarials for the treatment of uncomplicated malaria and describes the logistical difficulties and limitations of this methodology. Finally it highlights the importance of such knowledge in preventing resistance, in prolonging the utility of existing antimalarial drugs, and in ensuring that all individuals and populations suffering from malaria get the right malaria treatment at the right time.