Publication: Recommendations for the adjuvant use of the poly-antibiotic–resistant probiotic Bacillus clausii (O/C, SIN, N/R, T) in acute, chronic, and antibiotic-associated diarrhea in children: consensus from Asian experts
Issued Date
2020-12-01
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ISSN
20550936
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2-s2.0-85093985511
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Mahidol University
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SCOPUS
Bibliographic Citation
Tropical Diseases, Travel Medicine and Vaccines. Vol.6, No.1 (2020)
Suggested Citation
Jo Anne De Castro, Dhanasekhar Kesavelu, Keya Rani Lahiri, Nataruks Chaijitraruch, Voranush Chongsrisawat, Pramod Prabhakar Jog, Yun Haw Liaw, Gia Khanh Nguyen, Thi Viet Ha Nguyen, Uday Ananth Pai, Huu Nguyet Diem Phan, Seng Hock Quak, Pornthep Tanpowpong, Mary Jean Guno Recommendations for the adjuvant use of the poly-antibiotic–resistant probiotic Bacillus clausii (O/C, SIN, N/R, T) in acute, chronic, and antibiotic-associated diarrhea in children: consensus from Asian experts. Tropical Diseases, Travel Medicine and Vaccines. Vol.6, No.1 (2020). doi:10.1186/s40794-020-00120-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/60024
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Title
Recommendations for the adjuvant use of the poly-antibiotic–resistant probiotic Bacillus clausii (O/C, SIN, N/R, T) in acute, chronic, and antibiotic-associated diarrhea in children: consensus from Asian experts
Other Contributor(s)
De La Salle Medical and Health Sciences Institute
Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune
University of Medicine and Pharmacy Vietnam
Hanoi Medical University
National University Hospital, Singapore
King Chulalongkorn Memorial Hospital, Faculty of Medicine Chulalongkorn University
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Dr. D.Y. Patil Medical College, Navi Mumbai
Institute of Pediatrics
Pai’s Clinic
KPJ Sabah Specialist Hospital
Apollo Children's Hospital
Vietnam Aerospace Association
Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune
University of Medicine and Pharmacy Vietnam
Hanoi Medical University
National University Hospital, Singapore
King Chulalongkorn Memorial Hospital, Faculty of Medicine Chulalongkorn University
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Dr. D.Y. Patil Medical College, Navi Mumbai
Institute of Pediatrics
Pai’s Clinic
KPJ Sabah Specialist Hospital
Apollo Children's Hospital
Vietnam Aerospace Association
Abstract
© 2020, The Author(s). This paper proposes recommendations for probiotics in pediatric gastrointestinal diseases in the Asia-Pacific region. Evidence-based recommendations and randomized controlled trials in the region are included. Cultural aspects, health management issues and economic factors were also considered. Final recommendations were approved by utilizing a modified Delphi process and applying the Likert scale in an electronic voting process. Bacillus clausii was recommended as an adjunct treatment with oral rehydration solution for acute viral diarrhea. B. clausii may also be considered for prevention of antibiotic-associated diarrhea, Clostridium difficile-induced diarrhea, and as adjunct treatment of Helicobacter pylori. There is insufficient evidence for recommendations in other conditions. Despite a diversity of epidemiological, socioeconomical and health system conditions, similar recommendations currently apply to most Asia-Pacific countries. Ideally, these need to be validated with local randomized-controlled trials.