Publication:
Slow Acceptance of Universal Antiretroviral Therapy (ART) Among Mothers Enrolled in IMPAACT PROMISE Studies Across the Globe

Issued Date

2019-09-01

Resource Type

Article

ISSN

15733254
10907165

DOI

10.1007/s10461-019-02624-3

Other identifier(s)

2-s2.0-85070339824

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

AIDS and Behavior. Vol.23, No.9 (2019), 2522-2531

Suggested Citation

L. Stranix-Chibanda, S. Brummel, J. Pilotto, M. Mutambanengwe, V. Chanaiwa, T. Mhembere, M. Kamateeka, J. Aizire, G. Masheto, R. Chamanga, M. Maluwa, S. Hanley, E. Joao, G. Theron, N. Nevrekar, M. Nyati, B. Santos, L. Aurpibul, M. Mubiana-Mbewe, R. Oliveira, T. Anekthananon, P. Mlay, K. Angelidou, C. Tierney, L. Ziemba, A. Coletti, K. McCarthy, M. Basar, N. Chakhtoura, R. Browning, J. Currier, M. G. Fowler, P. Flynn Slow Acceptance of Universal Antiretroviral Therapy (ART) Among Mothers Enrolled in IMPAACT PROMISE Studies Across the Globe. AIDS and Behavior. Vol.23, No.9 (2019), 2522-2531. doi:10.1007/s10461-019-02624-3 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/51456

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Title

Slow Acceptance of Universal Antiretroviral Therapy (ART) Among Mothers Enrolled in IMPAACT PROMISE Studies Across the Globe

Author(s)

L. Stranix-Chibanda
 S. Brummel
 J. Pilotto
 M. Mutambanengwe
 V. Chanaiwa
 T. Mhembere
 M. Kamateeka
 J. Aizire
 G. Masheto
 R. Chamanga
 M. Maluwa
 S. Hanley
 E. Joao
 G. Theron
 N. Nevrekar
 M. Nyati
 B. Santos
 L. Aurpibul
 M. Mubiana-Mbewe
 R. Oliveira
 T. Anekthananon
 P. Mlay
 K. Angelidou
 C. Tierney
 L. Ziemba
 A. Coletti
 K. McCarthy
 M. Basar
 N. Chakhtoura
 R. Browning
 J. Currier
 M. G. Fowler
 P. Flynn

Other Contributor(s)

FHI 360
 Botswana Harvard AIDS Institute Partnership
 Centre for the AIDS Programme of Research in South Africa
 Frontier Science & Technology Research Foundation, Inc.
 Centre for Infectious Disease Research in Zambia
 UNC Project-Malawi
 University of Malawi College of Medicine
 Makerere University
 Kilimanjaro Christian Medical Centre
 Hospital Nossa Senhora da Conceicao
 Hospital Geral de Rio de Janeiro
 University of Zimbabwe
 University of California, Los Angeles
 St. Jude Children's Research Hospital
 National Institute of Child Health and Human Development
 National Institute of Allergy and Infectious Diseases
 Faculty of Medicine, Siriraj Hospital, Mahidol University
 Center for Biostatistics in AIDS Research
 Universiteit Stellenbosch
 Johns Hopkins School of Medicine
 Universidade Federal do Rio de Janeiro
 BJ Government Medical College
 Hospital Federal dos Servidores do Estado
 Chiang Mai University
 Perinatal HIV Research Unit

Abstract

© 2019, The Author(s). The PROMISE trial enrolled asymptomatic HIV-infected pregnant and postpartum women not eligible for antiretroviral treatment (ART) per local guidelines and randomly assigned proven antiretroviral strategies to assess relative efficacy for perinatal prevention plus maternal/infant safety and maternal health. The START study subsequently demonstrated clear benefit in initiating ART regardless of CD4 count. Active PROMISE participants were informed of results and women not receiving ART were strongly recommended to immediately initiate treatment to optimize their own health. We recorded their decision and the primary reason given for accepting or rejecting the universal ART offer after receiving the START information. One-third of participants did not initiate ART after the initial session, wanting more time to consider. Six sessions were required to attain 95% uptake. The slow uptake of universal ART highlights the need to prepare individuals and sensitize communities regarding the personal and population benefits of the “Treat All” strategy.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/51456

Collections

Scopus 2019