Publication: Risk factors and outcome of atypical acute post-streptococcal glomerulonephritis in pediatrics
Issued Date
2013-05-22
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ISSN
01251562
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2-s2.0-84877867383
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.44, No.2 (2013), 281
Suggested Citation
Satoru Takeno, Suwannee Wisanuyotin, Apichat Jiravuttipong, Chukiat Sirivichayakul, Kriengsak Limkittikul Risk factors and outcome of atypical acute post-streptococcal glomerulonephritis in pediatrics. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.44, No.2 (2013), 281. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/32338
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Title
Risk factors and outcome of atypical acute post-streptococcal glomerulonephritis in pediatrics
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Abstract
We conducted this study to identify the clinical features and risk factors for atypical acute post-streptococcal glomerulonephritis (APSGN). Thirty-five cases of atypical APSGN treated at Srinagarind Hospital during 2002-2009 were compared with 27 typical cases. The clinical symptoms, anti-streptococcal antibody titers, and laboratory data at the first hospital visit were compared between the two groups. A marked elevation in anti-streptolysin O (ASO) titer was seen more commonly in the atypical APSGN group than in the typical APSGN group (p=0.025). Significantly more patients in the atypical APSGN group had a high urine specific gravity, hematuria and pyuria than patients in the typical APSGN group (p<0.01, p<0.031, and p<0.046, respectively). A high ASO titer, high urine specific gravity, severe hematuria and pyuria early in the illness were suggestive of a higher risk for an atypical presentation.