Publication: Use of insecticide-treated school uniforms for prevention of dengue in schoolchildren: A cost-effectiveness analysis
Issued Date
2014-09-23
Resource Type
ISSN
19326203
Other identifier(s)
2-s2.0-84907470407
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
PLoS ONE. Vol.9, No.9 (2014)
Suggested Citation
Yesim Tozan, Pitcha Ratanawong, Valérie R. Louis, Pattamaporn Kittayapong, Annelies Wilder-Smith Use of insecticide-treated school uniforms for prevention of dengue in schoolchildren: A cost-effectiveness analysis. PLoS ONE. Vol.9, No.9 (2014). doi:10.1371/journal.pone.0108017 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/32984
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Use of insecticide-treated school uniforms for prevention of dengue in schoolchildren: A cost-effectiveness analysis
Abstract
Background: Dengue-related illness is a leading cause of hospitalization and death, particularly among children. Practical, acceptable and affordable measures are urgently needed to protect this age group. Schools where children spend most of their day is proposed as an ideal setting to implement preventive strategies against day-biting Aedes mosquitoes. The use of insecticide-treated school uniforms is a promising strategy currently under investigation.Methods: Using a decision-analytic model, we evaluated the cost-effectiveness of the use of insecticide-treated school uniforms for prevention of dengue, compared with a ''do-nothing'' alternative, in schoolchildren from the societal perspective. We explored how the potential economic value of the intervention varied under various scenarios of intervention effectiveness and cost, as well as dengue infection risk in school-aged children, using data specific to Thailand.Results: At an average dengue incidence rate of 5.8% per year in school-aged children, the intervention was cost-effective (ICER≤$16,440) in a variety of scenarios when the intervention cost per child was $5.3 or less and the intervention effectiveness was 50% or higher. In fact, the intervention was cost saving (ICER,0) in all scenarios in which the intervention cost per child was $2.9 or less per year and the intervention effectiveness was 50% or higher. The results suggested that this intervention would be of no interest to Thai policy makers when the intervention cost per child was $10.6 or higher per year regardless of intervention effectiveness (ICER>$16,440).Conclusions: Our results present the potential economic value of the use of insecticide-treated uniforms for prevention of dengue in schoolchildren in a typical dengue endemic setting and highlight the urgent need for additional research on this intervention.