Publication: Evaluation of adverse events and health-related quality of life in patients with colorectal cancer receiving ambulatory home-based chemotherapy in Thailand
Issued Date
2021-11-01
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ISSN
20541058
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2-s2.0-85112212606
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Mahidol University
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SCOPUS
Bibliographic Citation
Nursing Open. Vol.8, No.6 (2021), 3036-3044
Suggested Citation
Suwannee Sirilerttrakul, Noppaskan Wannakansophon, Pinyo Utthiya, Sineenuch Ckumdee, Patamaporn Tangteerakoon, Phichai Chansriwong Evaluation of adverse events and health-related quality of life in patients with colorectal cancer receiving ambulatory home-based chemotherapy in Thailand. Nursing Open. Vol.8, No.6 (2021), 3036-3044. doi:10.1002/nop2.1016 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/78909
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Title
Evaluation of adverse events and health-related quality of life in patients with colorectal cancer receiving ambulatory home-based chemotherapy in Thailand
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Abstract
Aims: To compare adverse events and health-related quality of life in ambulatory home-based chemotherapy with those in inpatient. Design: Prospective non-randomized observational study. Methods: Participants were divided into two groups according to patients’ preference receiving chemotherapy. Results: Sixty-four participants were enrolled in the inpatient, and 111 were in an ambulatory home-based chemotherapy. The frequency of anaemia, neutropenia and thrombocytopenia was significantly higher in inpatient group than in ambulatory home-based chemotherapy group (p <.001, <.001 and.002, respectively). Nausea, mucositis, and fatigue were more common in ambulatory home-based chemotherapy group than in inpatient group (p <.001,.022, and.005, respectively). Patients in the ambulatory home-based chemotherapy group showed higher social well-being (SWB) scores than inpatient group (coefficient 1.92, 95% confidence interval [CI] 0.65 to 3.19, p.003).