Publication: Estimating the transmission probability of human immunodeficiency virus in injecting drug users in Thailand
Issued Date
2001-01-01
Resource Type
ISSN
00359254
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2-s2.0-0035649577
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of the Royal Statistical Society. Series C: Applied Statistics. Vol.50, No.1 (2001), 1-14
Suggested Citation
Michael G. Hudgens, Ira M. Longini, M. Elizabeth Halloran, Kachit Choopanya, Suphak Vanichseni, Dwip Kitayaporn, Timothy D. Mastro, Philip A. Mock Estimating the transmission probability of human immunodeficiency virus in injecting drug users in Thailand. Journal of the Royal Statistical Society. Series C: Applied Statistics. Vol.50, No.1 (2001), 1-14. doi:10.1111/1467-9876.00216 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/26521
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Title
Estimating the transmission probability of human immunodeficiency virus in injecting drug users in Thailand
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Abstract
We estimate the transmission probability for the human immunodeficiency virus from seroconversion data of a cohort of injecting drug users (IDUs) in Thailand. The transmission probability model developed accounts for interval censoring and incorporates each IDU's reported frequency of needle sharing and injecting acts. Using maximum likelihood methods, the per needle sharing act transmission probability estimate between infectious and susceptible IDUs is 0.008. The effects of covariates, disease dynamics, mismeasured exposure information and the uncertainty of the disease prevalence on the transmission probability estimate are considered.