Publication: Risk of coronary artery disease in patients with idiopathic inflammatory myopathies: A systematic review and meta-analysis of observational studies
Issued Date
2014-01-01
Resource Type
ISSN
1532866X
00490172
00490172
Other identifier(s)
2-s2.0-84905216800
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Mahidol University
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SCOPUS
Bibliographic Citation
Seminars in Arthritis and Rheumatism. Vol.44, No.1 (2014), 63-67
Suggested Citation
Patompong Ungprasert, Promporn Suksaranjit, Ittikorn Spanuchart, Napat Leeaphorn, Nitipong Permpalung Risk of coronary artery disease in patients with idiopathic inflammatory myopathies: A systematic review and meta-analysis of observational studies. Seminars in Arthritis and Rheumatism. Vol.44, No.1 (2014), 63-67. doi:10.1016/j.semarthrit.2014.03.004 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/34790
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Title
Risk of coronary artery disease in patients with idiopathic inflammatory myopathies: A systematic review and meta-analysis of observational studies
Abstract
Objectives: To investigate the risk of coronary artery disease in patients with idiopathic inflammatory myopathies (IIM). Methods: We conducted a systematic review and meta-analysis of observational studies that reported odds ratios, relative risks, hazard ratios, or standardized incidence ratios comparing the risk of coronary artery disease in patients with IIM versus non-IIM participants. We searched published studies indexed in MEDLINE, EMBASE, and the Cochrane database from inception to December 2013 using the terms "coronary artery disease" OR "coronary heart disease" OR "myocardial infarction" OR "atherosclerosis" combined with the terms "dermatomyositis" OR "polymyositis" OR "Idiopathic inflammatory myopathy." Pooled risk ratio and 95% confidence interval were calculated using a random-effect, generic inverse variance method. Result: Overall, four studies were identified and included for data analysis. The pooled risk ratio of CAD in patients with IIM was 2.24 (95% CI: 1.02-4.92). The statistical heterogeneity of this meta-analysis was high with an I2of 97%. Conclusion: Our study demonstrated a statistically significant increased risk of CAD among patients with IIM. © 2014 Elsevier Inc.