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Iodine-catalyzed, one-pot, three-component aza-Friedel-Crafts reaction of electron-rich arenes with aldehyde/carbamate combinations

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dc.contributor.authorJaray Jaratjaroonphongen_US
dc.contributor.authorSuppachai Krajangsrien_US
dc.contributor.authorVichai Reutrakulen_US
dc.contributor.otherBurapha Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-06-11T04:36:57Z
dc.date.available2018-06-11T04:36:57Z
dc.date.issued2012-05-09en_US
dc.description.abstractIodine is shown to be an efficient catalyst for a one-step, three-component aza-Friedel-Crafts reaction of activated arenes or heteroarenes with benzyl or tert-butyl carbamates in combination with a wide variety of aldehydes in toluene under 'open-flask' and mild conditions. In the presence of 5 mol % of iodine in toluene at room temperature, the reaction gives the corresponding N-CBz or N-Boc protected α-branched amines, selectively, in good to excellent yields. © 2012 Elsevier Ltd. All rights reserved.en_US
dc.identifier.citationTetrahedron Letters. Vol.53, No.19 (2012), 2476-2479en_US
dc.identifier.doi10.1016/j.tetlet.2012.03.024en_US
dc.identifier.issn18733581en_US
dc.identifier.issn00404039en_US
dc.identifier.other2-s2.0-84859507206en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/13731
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84859507206&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleIodine-catalyzed, one-pot, three-component aza-Friedel-Crafts reaction of electron-rich arenes with aldehyde/carbamate combinationsen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84859507206&origin=inwarden_US

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