Publication: Assessment of Antifungal Activity of Aloe Vera Toothpaste against Candida Albicans
Issued Date
2020-03-04
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1757899X
17578981
17578981
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2-s2.0-85082945323
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Mahidol University
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SCOPUS
Bibliographic Citation
IOP Conference Series: Materials Science and Engineering. Vol.761, No.1 (2020)
Suggested Citation
S. Thaweboon, B. Thaweboon Assessment of Antifungal Activity of Aloe Vera Toothpaste against Candida Albicans. IOP Conference Series: Materials Science and Engineering. Vol.761, No.1 (2020). doi:10.1088/1757-899X/761/1/012007 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/54544
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Title
Assessment of Antifungal Activity of Aloe Vera Toothpaste against Candida Albicans
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Abstract
© Published under licence by IOP Publishing Ltd. Herbal products have been the basis for medical therapy and are noted as a form of alternative medicine. Modern medicine also employs the use of many herbal products for therapeutic purposes. Aloe vera is a medicinal herb whose mucilaginous gel is traditionally used to treat different diseases. It consists of the active compounds which include methylchromones, flavonoids, aloesin, aloe-emodin, sterols, amino acids, aloemannan, aloin, acemannan, aloeride, naftoquinones, saponin and vitamins. Aloe vera toothpaste, consequently, has been developed by the Thailand Institute of Scientific and Technological Research (TISTR) to fulfill a strategy of good oral hygiene. The aim of this study was to investigate the antifungal activity of aloe vera toothpaste against Candida albicans in vitro. Toothpaste containing 10% aqueous extract of the aloe vera leaf was prepared by TISTR. The toothpaste solution was prepared by mixing 0.66 g of toothpaste in 1 mL of sterile deionizing water. The suspensions of 107cfu/mL (equivalent to 0.5 McFarland Standard) of Candida albicans ATCC 10231 and 2 clinical isolates were prepared and added to toothpaste solution. After 50 sec, the final solution was transferred to D/E neutralizing broth and cultured at 37 °C for 24-48 h on Sabouraud dextrose agar. Sterile distilled water was used as a control. Colony forming unit (CFU) was counted after incubation. The result showed that aloe vera toothpaste had a significant inhibitory effect against tested candida species compared with a control. In conclusion, result from the present study is scientific information to prove that aloe vera toothpaste could be assigned as natural toothpaste against candida infection. With proper tooth brushing, it is a simple manner, leading to good oral care.