Publication:
Optimal cutoff titers for indirect immunofluorescence assay for diagnosis of scrub typhus

Issued Date

2015-11-01

Resource Type

Article

ISSN

1098660X
00951137

DOI

10.1128/JCM.01680-15

Other identifier(s)

2-s2.0-84945241907

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Clinical Microbiology. Vol.53, No.11 (2015), 3663-3666

Suggested Citation

Cherry Lim, Stuart D. Blacksell, Achara Laongnualpanich, Pacharee Kantipong, Nicholas P.J. Day, Daniel H. Paris, Direk Limmathurotsakul Optimal cutoff titers for indirect immunofluorescence assay for diagnosis of scrub typhus. Journal of Clinical Microbiology. Vol.53, No.11 (2015), 3663-3666. doi:10.1128/JCM.01680-15 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/36269

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Title

Optimal cutoff titers for indirect immunofluorescence assay for diagnosis of scrub typhus

Author(s)

Cherry Lim
 Stuart D. Blacksell
 Achara Laongnualpanich
 Pacharee Kantipong
 Nicholas P.J. Day
 Daniel H. Paris
 Direk Limmathurotsakul

Other Contributor(s)

Mahidol University
 Nuffield Department of Clinical Medicine
 Chiangrai Prachanukroh Hospital

Abstract

Copyright © 2015, American Society for Microbiology. All Rights Reserved. We determined the optimal cutoff titers in admission and convalescent-phase samples for scrub typhus indirect immunofluorescence assay using Bayesian latent class models. Cutoff titers of>1:3,200 in an admission sample or of a>4-fold rise to>1:3,200 in a convalescent-phase sample provided the highest accuracy (sensitivity, 81.6%; specificity, 100%).

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/36269

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Scopus 2011-2015