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Intracerebroventricular injection of CCK reduces operant sugar intake in pigs

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dc.contributor.authorB. A. Baldwinen_US
dc.contributor.authorS. Sukhchaien_US
dc.contributor.otherThe Babraham Instituteen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-07-04T07:34:14Z
dc.date.available2018-07-04T07:34:14Z
dc.date.issued1996-01-01en_US
dc.description.abstractPigs have a strong appetite for sugar solutions and readily learn to perform operant responses (pressing a panel with their snouts) to obtain glucose solution. Intracerebroventricular (ICV) injection of 1 μg CCK produced a significant (p < 0.01) reduction in the amount of glucose consumed compared with saline in the 30 min following injection. The reduction was a central effect as the same dose of CCK was ineffective given intravenously. The inhibition of intake was completely abolished by prior dosing with 100 μg of the CCKA receptor antagonist Devazepide given ICV. Devazepide itself had no effect on intake. The pig is a good experimental animal for the study of the regulation of sugar intake.en_US
dc.identifier.citationPhysiology and Behavior. Vol.60, No.1 (1996), 231-233en_US
dc.identifier.doi10.1016/0031-9384(95)02211-2en_US
dc.identifier.issn00319384en_US
dc.identifier.other2-s2.0-0030183288en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/17831
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0030183288&origin=inwarden_US
dc.subjectNeuroscienceen_US
dc.subjectPsychologyen_US
dc.titleIntracerebroventricular injection of CCK reduces operant sugar intake in pigsen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0030183288&origin=inwarden_US

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