Publication:
Controlled release of vancomycin from bone plate via layer-by-layer coating

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dc.contributor.authorNorased Nasongklaen_US
dc.contributor.authorKomgrit Eawsakulen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2020-01-27T07:49:29Z
dc.date.available2020-01-27T07:49:29Z
dc.date.issued2019-02-13en_US
dc.description.abstract© 2018 IEEE. Bone plate has been successfully used for bone fixation however, implant failures caused by infection often occurred with bacterial exposure. To address this issue, the bone plate was layer-by-layer coated by poly(lactic acid)/vancomycin (PLA/VCM) and also investigated important properties such as drug loading content and drug release. The amount of VCM on the surface after 42 layers of coating was 14, 131, and 350 μg for method A, B, and C, respectively. The coating was able to provide bacterial inhibition for 11, 15, and 15 days for method A, B and C, respectively. PLA/VCM-coated bone plates are the promising approach and will have broad applications in the orthopedic implants.en_US
dc.identifier.citationIEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED. Vol.2018-December, (2019), 264-267en_US
dc.identifier.doi10.1109/NANOMED.2018.8641661en_US
dc.identifier.issn21596972en_US
dc.identifier.issn21596964en_US
dc.identifier.other2-s2.0-85063034126en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/50258
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85063034126&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectEngineeringen_US
dc.subjectMedicineen_US
dc.titleControlled release of vancomycin from bone plate via layer-by-layer coatingen_US
dc.typeConference Paperen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85063034126&origin=inwarden_US

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