Publication: Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw
Issued Date
2004-01-01
Resource Type
ISSN
03788741
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2-s2.0-0345862085
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Ethnopharmacology. Vol.90, No.1 (2004), 69-72
Suggested Citation
S. Intahphuak, A. Panthong, D. Kanjanapothi, T. Taesotikul, C. Krachangchaeng, V. Reutrakul Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw. Journal of Ethnopharmacology. Vol.90, No.1 (2004), 69-72. doi:10.1016/j.jep.2003.09.026 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/21813
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Title
Anti-inflammatory and analgesic activities of Mallotus spodocarpus Airy Shaw
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Abstract
The chloroform extract from the roots of Mallotus spodocarpus was investigated for anti-inflammatory and analgesic activities in animal models. In acute inflammatory models, the extract significantly inhibited ethyl phenylpropiolate-induced ear edema and carrageenin- and arachidonic acid-induced hind paw edema in rats. In the chronic inflammatory model using the cotton pellet-induced granuloma in rats, the extract exhibited inhibitory activity on the formation of granuloma. The extract also elicited pronounced inhibitory effect on acetic acid-induced writhing response in mice in the analgesic test. The results obtained suggest marked anti-inflammatory and analgesic activity of the extract. © 2003 Elsevier Ireland Ltd. All rights reserved.