Publication: Vector competence for dengue-2 viruses isolated from patients with different disease severity
Issued Date
2020-10-01
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ISSN
20760817
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2-s2.0-85093982459
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Mahidol University
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SCOPUS
Bibliographic Citation
Pathogens. Vol.9, No.10 (2020), 1-13
Suggested Citation
Ronald Enrique Morales-Vargas, Dorothée Missé, Irwin F. Chavez, Pattamaporn Kittayapong Vector competence for dengue-2 viruses isolated from patients with different disease severity. Pathogens. Vol.9, No.10 (2020), 1-13. doi:10.3390/pathogens9100859 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/59878
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Title
Vector competence for dengue-2 viruses isolated from patients with different disease severity
Abstract
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Dynamics of dengue serotype 2 virus isolated from patients with different disease severity, namely flu-like classic dengue fever (DF) and dengue shock syndrome (DSS) were studied in its mosquito vector Aedes aegypti. We compared isolate infectivity and vector competence (VC) among thirty two A. aegypti-viral isolate pairs. Mosquito populations from high dengue incidence area exhibited overall greater VC than those from low dengue incidence area at 58.1% and 52.5%, respectively. On the other hand, the overall infection rates for the isolates ThNR2/772 (DF, 62.3%) and ThNR2/391 (DSS, 60.9%), were significantly higher than those for isolates ThNR2/406 (DF, 55.2%) and ThNR2/479 (DSS, 54.8%). These results suggest that the efficacy of dengue virus circulation was likely to vary according to the combination between the virus strains and origin of the mosquito strains, and this may have epidemiologic implications toward the incidence of flu-like classic dengue fever (DF) and dengue shock syndrome (DSS).
